● Secretary
   Ms. Misia Wu
   email: misia@gate.sinica.edu.tw
   Phone: (02) 2787-1306

● NRPB Program PI and Coordinator
   Dr. Ying-Ta Wu
   email: ywu@gate.sinica.edu.tw
   Phone: (02) 2787-1237

● Compound collection and development
   Dr. Shi-Shan Mao
   email: sshanmao@gate.sinica.edu.tw
   Phone: (02) 2787-1303

● Assay Development
   Dr. T-J Rachel Cheng
   email: tingjenc@gate.sinica.edu.tw
   Phone: (02) 2787-1267

● HTS and Cheminformatics
   Dr. Ying-Ta Wu
   email: ywu@gate.sinica.edu.tw
   Phone: (02) 2787-1237

● Medicinal Chemistry
   Dr. Jim-Ming Fang
   email: jmfang@ntu.edu.tw
   Phnoe: (02) 2787-1266
              (02) 3366-1663

 
 
 

Q1:Who can have access to uHTS services?
A1: Anyone having a project approved and supported by NSC or Other agencies can apply for uHTS. This program is supported by NRPB, so we give service priority to the research projects of NRPB.

Q2 : How to arrange for a uHTS assay?
A2: As a new user, you need to fill in an account application first. Please have your project information ready when working on both the Account and Project application forms. Once approved, you will be granted access to Project and Assy Managements, where you can add new project and new assay requests. You might have several assays in one project.
Note: A project is a titled research subject; an assay is one of the jobs executed in the project.

Q3: What is the status of your compound? what is the final DMSO concentration?
A3: Our compounds are solubilized in 100% DMSO and reformated to be 1 mM stock in online 1536-well plate.

 
 
 
Robotic System
 
The GRC’s ultra high-throughput screening systems (uHTS) has unsurpassed screening capacity,  accuracy, and flexibility.
                 


The uHTS ystem is equipped with:
  • 6-axis robot arm for dispatching screening process,
  • proprietary dispenser for handling various dispensing modes (250nL ~5uL),
  • pintool with 1536 precision pins (50nL slot) for transferring compounds, and
  • microplate CCD imager with various reading methods for reading assay result.
 
   
 
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